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plasmonics [2014/06/23 11:53]
Garrigues Yves
plasmonics [2015/06/16 15:12] (Version actuelle)
projet4-1a-2017 [Plasmonics]
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-==Teaching purpose==+===Course objectives===
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-Introduce the plasmons of surface, the located ​plasmons. ​Describe the behavior of the light in the interfaces or in an aqueous environment in the presence of metallic nanoparticles. Application ​to the biosensors.+To introduce ​surface ​plasmons and localized ​plasmons. ​To present plasmon excitation techniques with application ​to SPR biochips and antibody/​antigen kinetics
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-==Programme==+===Course outline===
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-  * SPR +  * Historical background. Optics of metals. Drude model. Intraband/interband transitionValidity ​of Drude model. Brendel-Bormann model. Metal interfaces. Evanescent waves. Surface plasmons. Excitation/​Resonance. ​Otto experiment. Kretschmann-Raether ​experimentOther excitation techniquesLabelless biochipsSPR biochips. Surface functionalization. Langmuir model. Antibody/​antigen ​kinetics. Sensograms. Biochip performances. Electrospotting. SPRi.
-  * Sensors with evanescent wave +
-  * Introduction on interferometric sensors (1/2h) +
-  * History ​Experiment ​of Otto. Experiment of Kretschmann-Raether +
-  * MultilayersMetallic nanoparticlesEvanescent waves, interferences and resonances +
-  * SPR and moleculesOptical biosensors conception +
-  * Plasmonics ​biochipskinetics ​and imaging+
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-==Application==+===Practical work===
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-  * TP / project ​(20 hours) ​on the experiments ​of Otto, Kretschmann-Raether +  * Practical works (hours): Numerical simulation and study of a time-resolved SPR with a FEM software (COMSOL) 
-  * Optical answer ​of colloidal metallic nanoparticles +  * Project (12 hours): design and construction ​of an SPR chip microfluidic cavity, characterization and observation of kinetic antibodies / antigens by optical imaging. 
-  * Molecular interactions without marker by SPRi.+\\ 
 +===Acquired skills=== 
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 +  * To understand principles of surface plasmon and localized plasmon resonances.  
 +  * To be able to use and design SPR biochips under specifications compatible with health IT.
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